Before 1980 Roughly through to 1980, vaccines were public goods. They were mostly made by national bodies who were publicly funded, although pharmaceutical companies were dipping their toes in the water. They were used for diseases that a national community thought were serious and worth getting vaccinated against – like polio. Few national communities would have … [Read more...] about Shifting Vaccine Confidence
Religion, Technology and Management
Religion Mention religion and the links between individuals and their creator, if they think they have one, come to mind. We imagine an individual fasting, meditating, or kneeling in prayer. It was more common in the past however to think of a people, like the People of Israel and their God. Our rulers, whether Kings or Pharaohs, stood in loco divinitas as the person … [Read more...] about Religion, Technology and Management
The Fault Lies in Our Stars
The Fault lies in our Stars not in Ourselves: Randomized Controlled Trials & Clinical Knowledge In the Beginning In 1947, a trial of streptomycin introduced RCTs to medicine. From then, through to their incorporation into the 1962 amendments to the Food, Drugs and Cosmetics Act, occasioned by the thalidomide tragedy, there were questions about the epistemological link … [Read more...] about The Fault Lies in Our Stars
Fawlty Stars
The argument in The Fault Lies in our Stars features in Chapter 6 of the forthcoming Shipwreck of the Singular. It was sent out for comment to the following, who were chosen mostly by Mark Wilson. The responses received are below: Corrado Barbui, Lisa Bero, Alan Cassels, Angus Deaton, Jean-Francois Dreyfus, Andrew Leigh (author of Randomistas), Silvio Garattini (& … [Read more...] about Fawlty Stars
The Raine in June Falls Mainly in …
June Raine featured in the international media last week as the public face of Britain's MHRA (drugs regulatory agency) when they became the first agency to license a Covid vaccine. A journalist, who had unearthed a letter of mine from 20 years ago, got in touch with me asking to talk by phone about whether I would be confident about JR's claims that we all could have … [Read more...] about The Raine in June Falls Mainly in …
Prescription for Sorrow – Patrick Hahn
This week Samizdat publishes its Fourth book - Prescription for Sorrow by Patrick Hahn, following on the heels of its Third book, the best-selling Malcharist. Jim Gottsteins's The Zyprexa Papers is an honorary Fifth. The book is immediately available on Amazon and we will look to get it installed on Kobo and Lulu also. For the moment therefore it may not be available in … [Read more...] about Prescription for Sorrow – Patrick Hahn
Frontiers in Psychiatry: Elena Vicario
Some weeks ago, following the publication of an article by Andrea Cipriani in their journal, Jim Gottstein and I wrote to the Frontiers in Psychiatry Bigwigs asking for the Cipriani article to be removed - Meta-Analytic SuperSpreader. They have since replied Vicariously through Elena Vicario. From: Editorial Office <editorial.office@frontiersin.org> Date: Tue, 3 … [Read more...] about Frontiers in Psychiatry: Elena Vicario
Michael Hengartner, Andrea Cipriani and Frontiers in Psychiatry
Meta-Analytic SuperSpreader outlined a disturbing sequence of events leading up to the publication of an article by Andrea Cipriani and colleagues effectively promoting the benefits of antidepressants. Andrea and colleagues are part of an Oxford University Precision Psychiatry 'lab'. The idea that this article in some way helps move us toward a precision psychiatry is … [Read more...] about Michael Hengartner, Andrea Cipriani and Frontiers in Psychiatry
PIMsPlus: Medication Reference Site
Taper MD today launched PIMsPlus.org, a new free searchable resource for safer medication use which is focused on Potentially Inappropriate Medications (PIMs): medications that should be used with caution in older adults because research and clinical experience with these medications have shown that the risk of adverse effects can outweigh the benefits. The aim of … [Read more...] about PIMsPlus: Medication Reference Site
Meta-Analytic Super-Spreader
In a recent post Infection Super-Spreaders, I outlined the disturbing publication of an article by Andrea Cipriani and colleagues that gives a green light to prescribing antidepressants to children. Prescribing antidepressants to children could even be part of Precision Psychiatry - a new Oxford University brand to complement Evidence Based Medicine. Concerned about … [Read more...] about Meta-Analytic Super-Spreader