David Healy

Making medicines safer for all of us

Adverse drug events are now the fourth leading cause of death in hospitals.

It’s a reasonable bet they are an even greater cause of death in non-hospital settings where there is no one to monitor things going wrong and no one to intervene to save a life. In mental health, for instance, drug-induced problems are the leading cause of death — and these deaths happen in community rather than hospital settings.

There is also another drug crisis — we are failing to discover new drugs. [Read more...]

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Harmatology: a New Science
June, 7, 2022 | 44 Comments

In 2008-2009, 7 young women died in a HPV vaccine trial in India. There was a backlash against the clinical trial industry.  Quite apart from Pharma trials, the National Institutes of Health (NIH) had 70 ongoing trials that were abandoned. It was clear, Indian investigators had to be taught how to assess awkward events properly. […]

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Mark and Barb and Eric and Carole
May, 30, 2022 | 13 Comments

If North Americans don’t know much about Asterix cartoons – see The Harmed, Europeans don’t know about MAD. This image was adapted by Nina Otulakowski from a front cover image in Mad, see below, featuring the 1969 Bob, and Carol, and Ted and Alice movie. Born in the USA Multi-Regional Clinical Trials (MRCT) was born […]

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The Harmed Throw Down a Gauntlet
May, 24, 2022 | 13 Comments

The Gauls in Pharmaland © Nina Otulakowski May 2022 This set piece featuring the heroes from Cause and Effect copies a scene from an Asterix and Obelix cartoon – the original is below. Few North Americans know about Asterix and Obelix, the irreverent Gauls, who almost single-handedly held out against the might of the Roman […]

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So Long and Thanks for all the Fish
May, 15, 2022 | 16 Comments

This image of Jorge Mario Bergoglio and Augusto Roux with Augusto as Obelix (of Asterix and Obelix fame), in the Roman Colliseum, will have to wait for a full explanation.  It will make sense in Argentina and Europe but not in North America.  A detailed explanation for North Americans will come next week.  The posts […]

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Post Covid Vaccine Neuropathic Arm
May, 10, 2022 | 14 Comments

This post is by Mary Lynch – see Credentials in Cause and Effect.  A neuropathic arm sounds like something terrible from an Edgar Allan Poe horror story.  Anette Diamond (name changed) is a 66 year-old woman. She has approved this post. She had been living with chronic low back pain and fibromyalgia for several years […]

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