On November 22nd the European Medicines’ Agency (EMA) is holding a workshop on access to the data from clinical trials. While there have been many efforts by many people over the years to make the clinical trial process more transparent, the EMA workshop has come about primarily following the efforts of Peter Gøtzsche of the Danish Cochrane Group and Peter Doshi and Tom … [Read more...] about Won’t Get Fooled Again? GlaxoSmithKline and Access to Data
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The St Bartholomew’s Day Massacre: Protestant Patients, Catholic Drugs
Margot's lover in La Reine Margot was one of the Huguenots who survived the massacre set in train by her brother Charles IX on St Bartholomew's Day in Paris in 1572. There are many politicians, bureaucrats, doctors and others, the Royalists, in a position to make a difference who know that psychotropic drugs can cause suicide or other serious problems but who instead attempt … [Read more...] about The St Bartholomew’s Day Massacre: Protestant Patients, Catholic Drugs
La Reine Margot: Data access, ghostwriting, suicide and mad reviewers
Another study giving a first hint of the findings in our 2012 Mortality in Schizophrenia paper (See The Madness of Psychiatry) was published in the British Journal of Psychiatry in 2006 - Lifetime Rates of Suicide in Schizophrenia. It took several years and some smuggling to get it into print. In the course of exploring the issues, it seemed useful to touch base with Herb … [Read more...] about La Reine Margot: Data access, ghostwriting, suicide and mad reviewers
Benefit Risk Madness: Antipsychotics and Suicide
Following the posting of The Madness of Psychiatry, there has been a flurry of activity in the twittersphere with Louis Appleby, the UK's suicide czar posting: What makes adolescents act on suicidal thoughts? New paper shows psychotic symptoms increase risk 20-fold. archpsyc.jamanetwork.com/article.aspx?a… You might get the impression from this that all patients have to do … [Read more...] about Benefit Risk Madness: Antipsychotics and Suicide
The Madness of Psychiatry
One hundred years ago patients with psychosis were 4 times more likely than the rest of their contemporaries to be dead at the end of their first 5 years of treatment. The main cause of death was tuberculosis. The asylum was a place where if you had the wrong genetic makeup you were at great risk of catching tuberculosis, particularly if you were a young woman. The advent of … [Read more...] about The Madness of Psychiatry
The Madness of Young People
In 1861 Benedikt Morel, a physician in France, described a terrifying new illness. It involved young people in their late teens or early twenties about to enter what should have been the prime of their lives who instead sank into a profound and seemingly incurable state of what he termed precocious dementia. Morel painted a picture of a terrifying and seemingly close to … [Read more...] about The Madness of Young People
The Madness of Carl Jung: A Dangerous Method
Carl Jung was one of Freud's earliest supporters and in many respects rivaled him in terms of influence. Some of their interactions provide the basis for the story behind the book and recent movie - A Dangerous Method. Just as Freud did, he famously analyzed himself and while doing so apparently became psychotic. His psychosis was however seen as a way to sanity - a forerunner … [Read more...] about The Madness of Carl Jung: A Dangerous Method
The Madness of Childbirth
The North Wales asylum made its way into my life by accident. The history department at Bangor University secured a grant to look at the social impact of the asylum. Looking at the records they collected, it was striking how people declared their madness a century ago – they tore off their clothes and escaped through windows, which they never do now. A quixotic database But … [Read more...] about The Madness of Childbirth
The Madness of North Wales
Influenced like many of my generation by the writings of Laing, Szasz, Illich, Jung and Freud, I studied medicine to do psychiatry. At the time research was becoming mandatory for anyone hoping to engage with the field. I chose to work on the serotonin system. But this was working on the mind as much as the brain; this was the serotonin system brought into view by LSD rather … [Read more...] about The Madness of North Wales
Dance With Python: Healthcare In Peril
This is the last in what was once the BarMittzva Romba series aimed at Bar(ack) & Mitt. These have now been renamed as a series of Dances - Dancing as fast as we can, Dance to the Music of Time, Dancing In The Dark, Dance of the Sugar Plum Fairies, & Shadow Dance. Between them they reprise the plot of Pharmageddon. In Malaysia, Dancing with Pythons is an art form. … [Read more...] about Dance With Python: Healthcare In Peril