Once is Never

This is the second of 3 posts laying out the philosophical basis for Rxisk.org which will be live in the next few weeks. The others are Cri de coeur & the Unbearable lightness of being. In Cri du Coeur I outlined a scenario in which a treatment that causes suicide when put into good trials without any manipulation of the data, any statistical artifice, or any ghostwriting might give rise to a … [Read more...]

Cri de coeur

This is the first of 3 posts laying out the philosophical basis for Rxisk.org which will be live in the next few weeks. The others are Once is Never & the Unbearable lightness of being. “[I suggest] a meeting with yourself and your reviewers. I have spoken in public on these issues and offered to speak on any platform. I’ve visited the MHRA [British equivalent of FDA]. Part of my motivation … [Read more...]

The day the Lyrics lied

This post was written by Dr Irene Campbell-Taylor, a former Clinical Neuroscientist and Assistant Professor of Medicine at the University of Toronto. It is essential to read the marketing copy of pharmaceutical companies with care and attention for critical hidden details. It is rare to find an announcement with such obvious errors and dangerous suggestions up front as those contained in the … [Read more...]

Every drink spiked

This post is written anonymously (see Petra’s story). I outlined how my daughter Petra came to take Cymbalta on this blog a few months ago (see Petra’s story; also see Symbolta of Sorts). This post tells of events that led to her coming off. Petra is an enthusiast for motor sport events. She has been on track days, hill climbs and driver training events. She is a member of an Italian car club. … [Read more...]

A Symbolta of Sorts

In the early 1990s, Prozac was riding high but Lilly were planning its successor. The leading candidate was duloxetine – a dual inhibitor of both serotonin and norepinephrine reuptake as the older tricylic antidepressants (TCAs) had been. The company approached me in 1992 to recruit patients to a clinical trial of the new drug but before the trial could start duloxetine was pulled from development … [Read more...]

Shocking the Homeland

The thriller Homeland reached its denouement in the UK at the weekend – in an Electroconvulsive Therapy (ECT) scene. Claire Danes, a Homeland security agent supposedly taking Clozapine to contain her paranoia has to distinguish reality from psychosis to save the United States (see Homeland Security). Quite obviously to anyone who knows anything about Clozapine, she was not taking it. She is having … [Read more...]

The factories of post-modernism

In the 1960s revolution was afoot. Antipsychiatry was born. The new revolutionnaries targetted medicalization and claimed mental illnesses didn't exist. Out of this cauldron, postmodernism was discovered. Postmodernism provided the basis for an ongoing guerilla war against capitalism and industrial society waged by social scientists, anthropologists and others trained in the humanities. Science … [Read more...]

May Fools’ Day

Following the long-standing tradition, dating back at least to Chaucer, of playing practical jokes on May 1, The Scientist clearly thought it would be a good idea to show the outside world that science doesn’t always have to be stuffy and picked the appropriate day to demonstrate the point (http://the-scientist.com/2012/05/01/data-diving/). May Fools' Day Joke Sadly, the joke has gone unnoticed, … [Read more...]