Editorial Note: I have to thank Ken Spriggs for pointing out the Humira in Ulcerative Colitis Review site. For anyone interested in AbbVie-ing and in Humira this site offers some sobering reading.
With the recent approval of Humira (Adalimumab) by the FDA, there is a growing need for ulcerative colitis patient reviews of their experiences with this medication. Like some other biologics, Humira helps to stop the communication of a specific part of the immune system’s inflammatory response.
Many UC’ers are concerned that immune suppresants such as Humira will stop their immune system from working. That is not entirely true. Humira’s main goal is to stop the TNF alpha section of the immune response. (If humira stopped everything in our immune systems from working…it would be game over for everyone real quick).
Although Humira was approved by the FDA much later than Remicade which is a similar immune suppressant medication, there has been research and studies with Humira as far back as 1999 when it was still under development.
Like all medications, doctors should be consulted considerably when the decisions are being made to potentially start medications. Humira is no different. There are many reported potential side effects, and you as a patient should be well aware of what these are.
If you have experience with taking Humira for treating your ulcerative colitis, please consider leaving a review of your experience on this page.
Jul 23, 2013 by Crystal
Country & City: Champlin, MN.
Humira has to be one of the worst medications I have taken for my UC. I developed Autoimmune Hepatitis from Humira and now have to be a slave to labs every two weeks, monitoring my liver, hoping that it will go away and stay gone. Not enough research has been done on this drug to know if the Autoimmune Hepatitis will remain a chronic condition, or go away now that I have stopped the medication. Be VERY cautious when taking Humira, and listen to your body – I was told that there was less than a 2% chance of having any liver problems, and look what happened to me. Be your own/best advocate especially when doctors won’t listen to you.
I hate it as much as prednisone
– See more at: http://www.ihaveuc.com/humira-reviews/#sthash.OFcW3LSa.dpuf
Jul 23, 2013 by Joanna
Country & City: Bethel park, pa
After my excruciating loading dose, i developed frozen joints and c diff after a day. I did not know humira could cause c diff or else i really doubt i wouldve taken it. Been struggling with that for the entire year since my loading dose in january. I only took that first day of doses- only three of the four because i fainted from the pain of the shots. I couldnt bare to take the last one. Definitely something i regret taking. I always hate seeing those untrue commercials of the happy humira patients because i have a feeling there is a way larger amount of unhappy humira patients.
The “gift” that keeps giving!
Jul 22, 2013 by Shelly Miller
Country & City: Maine
After becoming allergic to remicade and hitting another severe flare and waiting weeks for approval…I think it did stop the bleeding despite being allergic to it the whole time (6 months). I experienced lots of rashes, numbness, tingling, chest pain-even had to have heart stress test, nerve pain, my body is forever changed because of it.
I hope it works for others, but read all you can so you know what to expect for side effects and make an informed decision.
So far so good
Jul 22, 2013 by Jennifer
Country & City: GA
i have been on humira for approx 1 month now. not showing any vast improvement nor am i showing any major problems shown below (however i’m also noticing its around the 3-4 month mark where ppl seem to have difficulties). i will say my urgency has increased. i have about 15-20 second window before ill shit myself, and usually dont make it about 3x per week. take ty3 for pain (it slows my gut down too).
I haven’t had any lesions or fevers yet, however had to stop the 6MP immediately due to staph infection on my ankle WBC was 2 and hemoglobin was 7.8 (this was before humira though).
Ive been a lot worse, but definitely wont accept this to be “normal”. i have UC pancolitis and have tried all the sulfa and mesa drugs, canasa, rowasa, remcaid, uceris, apriso, asacol, etc. will update in another 2 months to see if i have any of the bad reactions around the same time period. hoping not… hoping this drug kicks in. dont have any options left other than surgery…
Too much too handle!
Jul 22, 2013 by Violet Sterba
Country & City: Washington
I do not like Humira period. It has made me miserable since starting it. I was diagnosed two years ago with UC and have been uncontrollable. Put on Humira 4 months ago and I have been sicker with everything else since. Had a 2 week long cold. Than had a nasty fungal infection that lasted two weeks in my mouth, basically thrush combined with multiple canker sores. Couldn’t eat without Vicodin. After a week into fungal infection, my sinuses flared and ended up with a 4 week long sinus infection. First 2 weeks was self care, finally broke down and went on antibiotics when I spiked a 103 temp and couldn’t move off my couch. Couldn’t get any air up my nose, nor could I get a sinus rinse to go up. Than the bumps started. Yes, I looked like a spotted leopard on my arms and legs. Erythema nodosum is what they call it. I have giant red patches all over my arms and legs that are hot, painful and sometimes itchy. My ankle is the size of a softball, literally no thanks to the bump on my tendon swelling. I could barely walk at one point the pain in my ankle was do severe. Back on Vicodin I went as well as a 2 antibiotic because the other antibiotic wasn’t working as well so I got to get a stronger one. Sinuses are clear now, start of week 5 but my spots are just as horrible. I’ve asked to be taken off Humira – denied. They actually want to increase my injections!!! Now I’m being referred to the University of WA to see their specialists. I have basically stopped all meds except for prednisone and I feel better. I felt worse on all the meds with no UC results. I think I’m going to hit this with diet now. I’m tired of the meds and broke cause I take so many. Humira may work for some but it’s been a horrible experience for me!
Nope Nope Nope.
Jul 22, 2013 by Geof
Have had UC proctitis since summer 2010 – Average 6-10 BM’s a day, pain between 5-9 every day,
I have tried near every medication and diet except remicade, nothing works and most of it makes me miserable.
After detoxing from 6mp for several months after it crashed my immune system and put me in the hospital with a 104 fever for a week they finally put me on humira.
Very bad decision.
I was on it for 3 months at my doctors request, and every day forward after starting in mid march was a spiraling loss of control. A constant daily sever shooting level 10/10 pain in the upper left side of my abdomen, it felt like I was constantly being stabbed. bowel movements 15-20 times a day with a 10 second urgency to shitting myself response (it was so bad i couldnt sleep) and diet did nothing. weight gain was around 10 lbs. loss of the will to leave the house, to eat anything, or to even live became a constant depressing mantra.
I stuck it out in may due to my gi clinic’s request, but it was like inducing torture to inject up… and i would not have lasted another 2 weeks at that rate. I quit taking injections mid may, and suddenly the clouds parted, and the first week i felt 10 % better, the next week 20% better, and so on and so on.
If that was a “light reaction” anything more would have been criminal.
It is now July 22 I am on Zero medications other than vicodin and occasional prednisone for when i have to leave the house… which is rare because this disease has ruined my life and humiliated me past the point of no return. but anyways… I feel 100% better after being on humira and 60% of normal, bm’s settling down to 6-10 a day depending on diet which takes me out of the colostomy territory.
Did not work for me
Jul 22, 2013 by Adam Scheuer
Country & City: Menlo Park, California USA
I decided (along with my GI) to attempt Humira as a treatment after failing with Remicade and 5-ASA’s and sulfasalazine, and prednisone and rowasa enemas.
Long story short is it gave me severe skin lessions to my hands, scalp, feet, and legs. Along with this, joint pain increased to a level I’d never known was possible. Within a few rounds of the injections, the decision was made to stop.
(just my experience, and I’m hoping that some people with UC have had great results with Humira, just didn’t work for me)
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