Adverse drug events are now the fourth leading cause of death in hospitals.
It’s a reasonable bet they are an even greater cause of death in non-hospital settings where there is no one to monitor things going wrong and no one to intervene to save a life. In mental health, for instance, drug-induced problems are the leading cause of death — and these deaths happen in community rather than hospital settings.
There is also another drug crisis — we are failing to discover new drugs. [Read more...]
MARTIN B. KELLER, M.D. Brown University Martin B. Keller Professor Emeritus of Psychiatry and Human Behavior [email protected] Martin Keller has made major research contributions to the understanding and treatment of mood disorders. He has performed research on the longitudinal course and neuropsychopharmacology of affective disorders and anxiety disorders and on the […]
Faced in 2012 with questions about the $3 Billion fine imposed on GSK – triggered by a sequence of events starting with Study 329, – is it just the cost of doing business? Andrew Witty snapped back: “Although corporate malfeasance cases end up looking very big, they often have their origin in just… one or […]
In addition to hosting the Panorama programs and The Famous Grouse history of Study 329, Study329.org has a comprehensive timeline on the origins of concerns about the SSRIs and the risk of suicide – initially with Prozac and subsequently with Paxil – Seroxat. The chronology is laid out year on year with key documents linked […]
Study 329 is probably the most famous clinical trial ever. It is one of the few to attract a Fraud action and is certainly the only one with a $3 Billion fine linked to it. See A Milestone in Drug Safety. The study began recruiting adolescents to Paxil, imipramine or placebo in 1994 and finished […]
Study 329: The final chapter coming soon Arguably the most controversial drug study ever, Study 329, published in July 2001: Concluded that paroxetine was a safe and effective medication for treating major depression in adolescents; Is still widely cited in the medical literature, providing physicians with assurance about the usefulness of paroxetine; Was criticized by […]