Go Ask Alice

Editorial Note: RxISK is all about people discovering things for themselves and alerting others to something that can make a real difference. There have been some wonderful examples outlined in posts here on RxISK from Anne-Marie Kelly’s discovery of a cure for Alcoholism – stop your SSRI and perhaps try a serotonin-3 antagonist like mianserin or ondansetron – to Samantha Dearnaley’s discovery … [Read more...]

RxISK STORIES: If you’re going to look after patients, Man up

Pharmalot has just posted a piece - 'Controversial FDA official, Tom Laughren, retires.' This is a must read for anyone with anything to do with mental health - both the post and the comments afterwards where some have posted that they still believe the Black Box warnings on antidepressants arose because of pressure from the Church of Scientology rather than in response to the data. Despite … [Read more...]

RxISK Stories: Listening to Parents

Anonymous When you lose a child or a partner from a rare illness, everyone is supportive, no-one denies you. They listen. But if a child dies from suicide or a complication of treatment with a drug especially a psychotropic drug no-one listens. Our culture has no place for this kind of death. They say maybe it’s for the best. He’d never have been able to face the life he’d have had - something … [Read more...]

RxISK Stories: Night of the Living Cymbalta – B’s story

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. I myself had been on and off a long series of antidepressants, but never had really dramatic withdrawal symptoms until I stopped the SNRI inhibitor Cymbalta. It started when I tried to step down from 120 mg per day, back to the standard 60 mg dose. From … [Read more...]

RxISK Stories: Cora’s story – a benzodiazepine story

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. In RxISK Stories, we regularly take you to dark places where few would wish to go. We have perhaps become too used to the horrific consequences of medicines going wrong that we fail to appreciate how off-putting this sequence of posts can be. It is like a … [Read more...]

RxISK Stories: Gambling on the side effects of antidepressants – does Pfizer play dice?

This piece by Daniel O'Sullivan was first posted on Crikey.com. Our interest was stimulated by a query to RxISK from Daniel who had been told by the Australian regulator (the TGA) that they only had one report of this. Looking for gambling in RxISK, gives 1 case in Australia, but 4 cases of pathological gambling - more than from all the rest of the world combined, and 8 cases of impulsive … [Read more...]

RxISK Stories: Weight gain on thyroxine

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. If there is one thing most doctors think they know its that weight gain can be caused by an underactive thyroid and having an overactive thyroid leads to weight loss. So the thyroid hormone, thyroxine, will lead to weight loss. And magazines, newspapers and … [Read more...]

RxISK Stories: Smoke & Pfizer get in your eyes

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. On March 15, Out of My Mind was published on davidhealy.org. This was one of the first RxISK stories. At the moment it is the blog post that has attracted the most comments. The comments are worth reading - there is close to universal recognition of … [Read more...]

RxISK Stories: The Myth of the Magic Bullet – Flox Tox

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. In July this year, Antimicrobrial Agents & Chemotherapy had an article - Fluoxetine is a Potent Inhibitor of Coxsackievirus Replication by Zuo J, Quinn KK and colleagues. "No antiviral drugs currently exist for the treatment of enterovirus infections, … [Read more...]

RxISK Stories – Facts about FACS

This blog post has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. Janet's Story I was diagnosed with epilepsy at the age of 14. After trying different drugs my seizures were controlled by a combination of Phenytoin (Epanutin) and Sodium Valproate (Epilim). What they didn’t tell me was that Sodium Valproate carried the … [Read more...]

RxISK Stories – Azathioprine withdrawal

This post was written by Ken Spriggs and comes from his DIYEHR (do it yourself electronic health record) site, and has first been published on the RxISK.org website. If you would like to comment on this post, please do so using this link. It brings out nicely how some people are only aware of the problems their drug causes when they stop. This is particularly true for people taking statins, but … [Read more...]

RxISK Stories: Withdrawal from antidepressants – V’s story

[For the next few weeks, this blog will take a feed from RxISK.org of RxISK stories. If you would like to comment on this post please do so on the RxISK website using this link. RxISK is open to stories from anyone on drugs who have adverse events and are in need of answers or from doctors managing adverse events on any medical drugs]. Question from V This is what V wrote on filing a RxISK … [Read more...]

RxISK Stories – Withdrawal from Clopidogrel

[For the next few weeks, this blog will take a feed from RxISK.org of RxISK stories, alternating with posts challenging Barack and Mitt to get to grips with healthcare costs. RxISK is open to stories from anyone on drugs who have adverse events and are in need of answers or from doctors managing adverse events on any medical drugs]. Query from Fiona Barton  Dr Healy, a friend suggested I email … [Read more...]