Psychiatrist. Psychopharmacologist. Scientist. Author.
Editorial Note: A riff by Laurie Oakley on the issue of Rape and Consent. See Laurie's recent post on RxISK - Over the Top. Tackling Medical Power and for pharmaceutical lawyers on the issue or Rape and Consent - see Dangerous Liaisons II. It should be read in conjunction with Doctors Writing Scary Scripts: Saving Grace - on RxISK We are interested in any additions anyone - even The Chester … [Read more...]
Editorial Note: This is the eighteenth post in the Persecution series, and a sequel to Dangerous Liaisons. See Brand Fascism for a listing of prior posts in the sequence. Slightly over a week ago in New York I was subject to a blizzard of questions from a lawyer for Forest, who taking great pleasure in using the word Fucked in a deposition asked among others questions whether it was … [Read more...]
This is the seventeenth in the Persecution Series. See Brand Fascism for a listing of prior posts in the sequence. In the novel Les Liaisons Dangereux, later the movie Dangerous Liaisons, the Marquise de Merteuil engages the Vicomte de Valmont to corrupt the incorruptible Madame de Tourvel..... From 1951, a system designed for heroin and cocaine addicts - prescription-only status - was … [Read more...]
The Events in Paris have led to a brief interruption to the Persecution Series although this post could have been termed Brand Fascism II. Illustration: Data Wars, 2012 © Billiam James The day after the Charlie Hebdo shootings in Paris, Nicholas Sarkozy stood on the steps of the Elysee Palace and said "This [the shootings] is a declaration of a war on civilization … [Read more...]
This is the Sixteenth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, of which there were eight in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , The SUI Cide … [Read more...]
This is the Sixteenth Modern Myth featuring Crusoe. The Persecution series resumes next week with Brand Fascism. The clinics were different now to what they had been. Hands on Fire The woman walked in, glancing at her hands as she came. Crusoe already knew what she would say. In days gone by peripheral neuropathies were rare. You saw one a year, perhaps in older people – more often women … [Read more...]
This is the Fifteenth Modern Myth, featuring Crusoe. The rest can be accessed under the modern myth tag. There will be another next week. The Pharma Sub-Series of the Persecution Murder Mystery will resume in the first week of the New Year. A Strange Man It was a time when Crusoe managed to be in Europe in Septembers. In 1957, interested in the fuss surrounding the new tranquilizers, she … [Read more...]
This is the Fifteenth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, of which there were eight in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , The SUI Cide … [Read more...]
This is the Fourteenth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and eight in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , The SUI Cide Note & SUI … [Read more...]
This is the Thirteenth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and seventh in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , The SUI Cide Note & SUI … [Read more...]
This is the Twelfth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and sixth in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat, The SUI Cide Note, SUI Cide or … [Read more...]
This is the Eleventh in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and fifth in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , The SUI Cide Note & SUI … [Read more...]
This is the Tenth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and fourth in the SUI Cide Series SUI Cide in Betsi, SUI Cide Trick or Treat , & The SUI Cide … [Read more...]
This is the Ninth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor, and third in the Suicide Series SUI-Cide in Betsi, SUI-Cide Trick or Treat Dr Higgo's Headache I was … [Read more...]
This is the Eighth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor and SUI-Cide in Betsi as well as the Second in the SUI-Cide series. The SUI in this case was being … [Read more...]
This is the Sixth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, Persecution: Black Riders in the Shire & Persecution: Rumbles from Mordor. When something serious goes wrong in healthcare it is standard to have a Serious Untoward Incident (SUI) … [Read more...]
This is the Sixth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who, & Persecution: Black Riders in the Shire. This completes the scene setting. Next week the posts will get down to the gritty-nitty. The Shire - Bangor - is to the North West of North … [Read more...]
Fifth in the Persecution Series, after The Persecution of Heretics, The Persecution of Vulnerable Adults, Harassment from the BBC to GMC, Harassment from Rolf Harris to James Coyne to Doctor Who. On the left is a map of North Wales, on the right Middle Earth from Lord of the Rings. Tolkien based his story on North Wales geography, with the Hergest Unit based right in the middle of the … [Read more...]
This is the fourth in the Persecution Series - a continuation of the letter to the H of Commons posted earlier this week. Double click on the image to view the words and the detail. Abuse is always Repeated I was referred to GMC some 8 years ago. Then the referral came from David Nutt and Guy Goodwin, professors of psychiatry in Bristol and Oxford, who as the basis of the complaint used an … [Read more...]
For those of you who like Breaking Bad, this the third in the Persecution Murder Mystery series. Without giving away the plot, it jumps right to last week. It has been adapted from a letter to members of the House of Commons committee on harassment in the NHS. The second part of the letter will feature later in the week - Harassment: From Rolf Harris to James Coyne and Doctor Who. Double click on … [Read more...]
For anyone bereft since Breaking Bad came to an end, this is a second installment in The Persecution of Heretics Murder Mystery series. Episode one can be seen here . The harassment of healthcare staff has been a backburner in British news recently. There have been a series of pieces in the Daily Mail, usually to the forefront of everything in healthcare, and the BMJ. A House of Commons … [Read more...]
Editorial Note: This is the start of a series that will likely run through to the End of the Year. For those of you who like Murder Mysteries, this is one. Please comment, speculate and help put a new source of harassment and intimidation properly on the map. This post accompanies a talk I gave at the Hay on Wye HowTheLightGetsIn Festival this May, called The Persecution of Heretics. … [Read more...]
Editorial Note: This is the last in the Doctor Munchausen series. A new strand on the Persecution of Heretics will start soon. The image is Paul Klee's Drawing for the Dance of a Grieving Child. Being Irish makes it possible to tackle certain things - or now possible. The question of the Catholic Church for instance and its handling of children, whether their abuse at the hands of pedophile … [Read more...]
Editorial Note: This piece was first submitted to the J of Mental Health in 1997 and two other journals later that year - with Marie Savage and Phil Thomas as co-authors. The reviewers were affronted - one figured mental health was likely no worse than the rest of medicine. Unable to find a home, it migrated to become a chapter in the third edition of Psychiatric Drugs Explained. Those not … [Read more...]
Editorial Note: This is the sixth in a Dr Munchausen series of posts. It was originally going to be entitled 'Dr Munchausen joins your local Hospital Board'. Crash & Holocaust Denialism In JG Ballard's novel Crash covered in the last post, we slip from the solid world in which we think we move to a dreamworld - the dreamworld in which we are now living. In this dreamworld perceptions connect … [Read more...]
Editorial Note: This is the fifth in a series of Doctor Munchausen posts that include: Dr Munchausen, I presume Dying for a Cure Dear Luise Father Munchausen They followed a Sense about Science series of posts that included: Sense about Science: Follow the Rhetoric Sense about Science: First Admit no Harm Sense about Science: Follow the Lawsuit Sense about Science: Follow … [Read more...]
Editorial Note: This is the fourth of seven Doctor Munchausen posts - Doctor Munchausen, I presume, Dying for a Cure, Dear Louise and the forthcoming Doctor Munchausen as a Sense about Science Trustee, and Doctor Munchausen Joins your local Hospital Board. I’ve had some criticism of the recent Doctor Munchausen posts. They’re not fair on doctors. Many people have told me of lives saved by … [Read more...]
Editorial Note: This is a third post in the six post Doctor Munchausen series. See Doctor Munchausen, I Presume and Dying for a Cure. A variation on this post first featured on RxISK.org some months ago Dear Luise by Dorrit Cato Christensen is one of most extraordinary books about healthcare ever written. Medical books are usually about great discoveries, great endurance, or triumph in one … [Read more...]
Editorial Note: This is the second in a Doctor Munchausen series of posts - meditations on the fact that medicine is likely the place where the greatest amount of abuse on earth happens - but no-one notices and no-one intervenes. The post below comes from the foreword to Dying for a Cure, Rebekah Beddoe's book on what happened her when she fell into the clutches of a doctor. The book came out … [Read more...]
Editorial note: As Britain descends into an orgy of handwringing about the abuse of vulnerable people, this is the first of several posts to tackle the issue In 2000 when I gave a lecture on Psychopharmacology and the Government of the Self at the invitation of the University of Toronto, I ran into a problem. In the public domain our shared difficulties were because of this lecture. In fact, … [Read more...]
Editorial Note: This is the second part of a Motivational Interviewing series crafted by Johanna Ryan and Ken Spriggs. Do you know the locations of all the best bathrooms? Do you often take a seat near the exit, just in case? Do you excuse yourself often to use the bathroom? Do you ever skip meals, or avoid certain foods, to avoid multiple bathroom trips? Those are questions from … [Read more...]
Editorial Note: This is the fourth of four posts about the links between Sense about Science and AllTrials. The first was Follow the Rhetoric. The Second was First Admit no Harm. The third was Follow the Lawsuit. The simple act of defining doctors or patients concerned about adverse events as “critics” is a rhetorical stroke that marginalizes concerns - makes you a one percenter rather than … [Read more...]
Editorial Note: This is a third in a series of posts about Sense about Science and Access to Clinical Trial Data that began with Follow the Rhetoric and followed up with First Admit no Harm. There are some facts in the last few posts. There are also some extrapolations that may not be right. Tracey Brown has gone on the Parliamentary Record to make clear what AllTrials are asking for - its … [Read more...]
Editorial Note: This is a second post exploring Sense about Science. The first post Follow the Rhetoric is here. Anyone interested in Pharma will know about its ability to Astroturf – to create patient organizations whose role is to promote an illness or subvert an existing one. Creating awareness of conditions sells drugs. On a Higher Astral Plane Less well known is what happens at a … [Read more...]
Editorial Note: This is the first of four posts about the link between Sense about Science and AllTrials triggered by the post Fucked and comments afterward by Ben Goldacre, Tracey Brown and others which raised these links. My first contact with Sense about Science was linked to the Simon Singh affair. Singh had made some relatively innocuous statements about chiropractic and been sued for … [Read more...]
[First published in the PLOS Blog. Click here for the original post.] Things were looking good recently in Europe for data transparency, a necessary, albeit not sufficient, tool to promote integrity of pharmaceutical data. The European Court’s Vice-President overturned in November 2013 two lower court interim suspensions of EMA’s data access decision in relation to Abbvie’s drug Humira and … [Read more...]
Editorial Note: Motivational interviewing began as a technique to help opiate or nicotine addicts or alcoholics. The idea was to move them through contemplation of the possibility of change, to having an action plan and then acting. It recognized that there was no point just arguing that addiction was wrong - you had to understand a person as well as the understood themselves to be able to get … [Read more...]
Editorial Note: Apologies for the Language A year and a half ago this blog ran a series of posts about access to clinical trial data – reporting on how industry were going to engineer the appearances of transparency. See Won't get Fooled Again, Access to Clinical Trial Data, and The Data Access Wars. Do Academics have Wild Dreams? Several months later, soon after being fined $3 Billion, GSK … [Read more...]
Editorial Note: It's common to find those behind Global Mental Health say that they might not originally have believed in the reality of mental illness and the efficacy of treatment but they do now. This and two following position pieces don't come from the same conversion perspective. I have always believed in the reality of mental illness and the efficacy of treatment. Nevertheless the … [Read more...]
Editorial Note: Another study published this week suggests that the issue of birth defects on antidepressants rather than suicide or homicide may yet end up as the Mark of Cain by which these drugs are remembered. This post appeared on RxISK.org first. Hush, little baby, don't say a word, Mama's gonna buy you a mockingbird. If that mockingbird won't sing, Mama's gonna buy you a diamond … [Read more...]
A lot people it seems have been singing and dancing in the street at news last week that AbbVie the pharmaceutical company that make Humira have dropped a legal action against the European Medicine’s Agency (EMA) that was aimed at blocking any access by researchers or others to their clinical trial data. Stacey of Arc Not everyone will be pleased though. Stacey London might wonder whether she … [Read more...]
Editorial Note: No one outside the UK may be paying any heed to the all-consuming debate within Britain about the referendum on the future of Scotland. Everything comes back to this. Corporations have been saying they'll pull out if Scotland leaves the UK (Standard Life) or that they'd prefer if Scotland left (British Airways). The EU have said Scotland would have to wait 5 years to apply to join … [Read more...]
Editorial Note: This prescient post written by Phil Booth was posted on OpenDemocracy.net under the title Your medical data - on sale for a pound on August 9th 2013. The original intention was to link it into the AbbVie debate about access to clinical trial data - as an ironic contrast. That opportunity passed - but a stopped clock throws up the right time twice a day. In recent weeks in … [Read more...]
Editorial Note: Richard commented on Peter Gotzsche's recent post Psychiatry Gone Astray. He was invited to develop his comment and does so here. My name is Richard Lawhern. I advocate for nearly 5,000 chronic pain patients as a volunteer moderator and content writer at "Living With TN", a social networking website. We support people with Trigeminal Neuralgia - the worst pain known to medical … [Read more...]
Editorial Note: Two weeks ago we ran Peter Gøtzsche's Psychiatry Gone Astray. There was a context - a Danish doctor had been found responsible for the suicide of a young man put on antidepressants. This and Peter's article stirred up debate in Denmark drawing a hard to credit defensive response from senior Danish Psychiatrists. Peter's blog was critiqued by George Dawson on Real Psychiatry. An … [Read more...]
Editorial note: This post is copied from RxISK Stories where there will be 5 posts this week on aspects of Enduring Sexual Dysfunction after treatment, covering the issues below. Wikipedia Stumbles and Falls Wikipedia used to host a valued page on Post-SSRI Sexual Dysfunction (PSSD). On January 27th this was taken down. A Post-Finasteride Syndrome page has also been taken down. On … [Read more...]
Editorial Note: This is cross-posted from 1boringoldman - Reassure Us. It tackles the most important issue in healthcare and one of the most important in politics. GSK have clearly persuaded Ben Goldacre, Iain Chalmers and David Cameron, and J&J have persuaded Harlan Krumholz and Barack Obama that their model of Data Access - the AbbVie model - is the only game in town. See The House of … [Read more...]
Editorial Note: The marketing of pharmaceuticals avails of something given to no other area of marketing - the product is made available on prescription-only. In this post Johanna Ryan, from RxISK's Community Advisory Board, spells out the risks this gives rise to. This is a theme that has come up often and one we will return to. Direct to Consumers? If you live in the USA, I don’t have to … [Read more...]
Editorial note: We follow up the Guilty post last week with a piece written by Peter Gotzsche that has caused a stir in Denmark and provoked some of the Danish professors he critiques to respond. At the Nordic Cochrane Centre, we have researched antidepressants for several years and I have long wondered why leading professors of psychiatry base their practice on a number of erroneous myths. … [Read more...]
Days of Reckoning? A little over a year ago, there was consternation in psychiatric circles as a French psychiatrist, Daniele Canarelli was found guilty after her patient hacked a man to death. She had not recogized the hazard he posed. Doctors didn't like the implications they saw. In a series of lectures I have raised the question as to how long it might be before a doctors would be found … [Read more...]
Editorial Note: In an End of Year post on RxISK, the concept of a Drug Traffic Accident was introduced. This can refer to being run over by a drug, sometimes called side effects, or adverse events, or adverse drug reactions or it can refer to the trafficking of drugs. This post covers both types. The first part is written by David Antonuccio and the second by the Editorial Board of the New York … [Read more...]
Crusoe and Hans grew up together. Crusoe’s father encouraged her to believe she could do anything she put her mind to. Han’s father, Peter, was a story-teller who delighted both children with his stories, especially during the long evenings at the onset of Winter. He told them about the Microbe Hunters who discovered the causes of diseases and laid the basis for new cures. But their favourite … [Read more...]
Editorial Note: This is based on the Finnish National Epic, the Kalevala. The image comes from the series painted by Axel Gallen to illustrate the Kalevala. Crusoe spent years trying to make a Medicine Maker. She was finally successful at the end of a long Winter just as the first signs of growth appeared on the trees. Everyone for miles around came when they heard the news. People with oozing … [Read more...]
Editorial Note: Crusoe has not been lying low since The Shipwreck of the Singular and The Girl who Wasn't Heard When She Cried Wolf. Check these out for previous Crusoe posts. The AbbVie story calls for a decent myth. Here is a start. Sink all Vaccines to the Bottom of the Sea? Crusoe was listening to Oliver give out. "They called me yesterday evening", he said, "to tell me about the vaccination … [Read more...]
Editorial Note: Three months ago we launched an AbbVie campaign and followed it up with a petition calling on AbbVie ad InterMune to drop their action against EMA. The hope was to raise awareness of this critically important issue that had been sailing beneath the radar. Over 6000 of you from more than 120 countries responded. This interim judgement is not a victory. It may be more a stay of … [Read more...]
A century ago Freud and Jung made us aware of the biases underpinning what patients say. Not everything should be accepted at face value. In particular claims of abuse may not be based on reality. We needed experts – analysts – they claimed to tease out what is real from what is not. The Catholic Church was once intensely hostile to Freud, but when it came to child abuse adopting a Freudian … [Read more...]
Anonymous Notes of a Paxil Guinea Pig What does GSK owe to the youngsters in its infamous Study 329 who became suicidal while taking the company’s paroxetine (Paxil/Seroxat)? As someone who was briefly a GSK Guinea Pig, I’d say the most important thing they’re owed is the truth. It’s a highly delinquent debt – but it’s not too late for GSK to pay up. I took part in a study of Paxil back in … [Read more...]
Editorial Note: This post is about midway through a series of posts that are broadly part of the AbbVie series. The series began with GSK's Transparency and Access Journey, moved on to The House of GSK and will have at least two more posts after this. Reading the Minneapolis StarTribune, it was the reference to privacy that clinched it. Facing a sexual abuse lawsuit, the archdiocese of St … [Read more...]
In a just published article in the BMJ, Peter Doshi notes how in recent months the English pharmaceutical company GlaxoSmithKline (GSK) have assiduously portrayed themselves as advocates of transparency and in support of access to clinical trial data. Well in support of 'Responsible Access'. Responsible essentially means that a researcher commits to the primacy of RCTs and statistical … [Read more...]
Editorial note: a slight variation of this appeared last week on The Conversation. In 2010, the European Ombudsman ruled that the European Medicines Agency should open access to clinical trials data when companies applied to get their drugs on the market. The ombudsman decided public health was more important than considerations of commercial confidentiality. In February this year, the US … [Read more...]
Editorial Note: Leah Cowan and Ancel-la Santos from Health Action International wrote this post covering the release of a HAI position paper on Access to Clinical Trial Data. HAI have been to the forefront of the move to patient reporting of Adverse Events. It has a position as a partner with the European Consumer Organization (BEUC) in support of EMA in the current legal action triggered by … [Read more...]
Editorial Note: This post has been put together by Peter Goetzsche and David Healy Dear Dr Goetzsche ... "At GSK we firmly believe that making more information available, including clinical study reports and anonymised patient-level data, will enable researchers to study the science behind today’s medicines more closely, to learn more about them and how they can best be used. For GSK … [Read more...]
SHIT stands for Secret Health Ingredient in Treatment - see SHIT Happens. In the early twentieth century SHIT was some supposedly secret magic chemical. In the early twenty-first century SHIT is important information about adverse effects of a drug that has been kept hidden. In SHIT Happens, we reported that RxISK has adverse event data on a range of GSK, Pfizer, Lilly and Merck drugs, drawn … [Read more...]
A century ago, a distinction was drawn between the ethical pharmaceutical industry and the patent medicines industry. Ethical companies specified what was in their medicines, whereas the patent industry kept the details hidden. The Birth of Pharma The patent medicines industry flourished on the back of a promise that some Secret Health Ingredient in their Treatment (SHIT) would transform us. … [Read more...]
Editorial Note: This is a cross post from 1boringoldman's Wisdom of the Dixie Chicks. It raises questions about a Lancet editorial jointly written by GSK and AllTrials it would seem. It calls on Iain and Ben to tell us what they are up to. So far there appears to be no clear response from AllTrials. There is an ambiguous message Here. This repost omits the image of a Trojan Horse and a … [Read more...]
Controlled trials are universally touted as providing gold standard information on drugs. Doctors are routinely taught to disbelieve the evidence of their own eyes and trust in controlled trials instead. Governments in North America and Europe are forcing patients to participate in controlled trials — saying that you get better care in a controlled trial — and claiming that participation is also … [Read more...]
Editorial Note: There is a widespread impression that the pharmaceutical industry are split on the issue of access to clinical trial data with the bad guys like AbbVie taking legal actions to block access and the good guys like GSK in favor of transparency. An editorial like this one from GSK's James Shannon in the Huffington Post on September 3rd might support such impressions. See Neal Parker … [Read more...]
Editorial Note: This is the second part of our effort to "translate" Neal Parker's recent presentation in Bruxelles. The first half is here Neal Parker Avoiding Adverse Events. Reading the first half and Neal Parker's original transcript - available here - will give lots more material for the Caption Competition below. The least dramatic moment in Mr Parker's talk laying out Pharma's position on … [Read more...]
Editorial Note: Neal Parker, Section Head Legal, Biologics Strategic Development at AbbVie, was an industry representative on a panel organized by EFPIA - The European Federation of Pharmaceutical Industries and Associates on August 27th in Bruxelles. In two posts AbbVie's Mission to Discover New Diseases and AbbVie's Mission to Discover New Patients, we gave a transcript of his talk with some … [Read more...]
Editorial Note: Neal Parker, Section Head Legal, Biologics Strategic Development at AbbVie, was an industry representative on a panel organized by EFPIA - The European Federation of Pharmaceutical Industries and Associates on August 27th in Bruxelles. Parker started off with a wonderful Freudian slip saying that AbbVie's mission is to discover new diseases and ends with another - that AbbVie's … [Read more...]
Editorial Note: Neal Parker, Section Head Legal, Biologics Strategic Development at AbbVie, was an industry representative on a panel organized by EFPIA - The European Federation of Pharmaceutical Industries and Associates on August 27th in Bruxelles. Parker started off with a wonderful Freudian slip saying that AbbVie's mission is to discover new diseases. A video of the meeting is linked to … [Read more...]
Several weeks ago Canadians woke up to a Globe and Mail article saying that the pharmaceutical company Eli Lilly, who are based in Indianapolis, was suing their Government for $500 million for loss of revenues linked to the loss of patents on two of its drugs - Zyprexa and Strattera. "The drug giant alleges that the loss of its patents violates Canada’s obligations under international treaties, … [Read more...]
Editorial Note: This post is taken from a more complete article published in BMJ today authored by Nigel Hawkes. It tells of a recent European meeting on access to clinical trial data. The meeting had input from AbbVie who it seems shocked everyone in the room shocked with their disregard for patient safety. The details here make it very clear why we need to petition AbbVie to drop their … [Read more...]
RxISK has started a petition on Change.org which will go to Richard Gonzalez CEO of AbbVie, and Daniel Welch CEO of InterMune, who are at present taking a legal action to block the European Medicines Agency's policy of open access to clinical trial data. The reason to petition is in this post Let's do the AbbVie again and the Petition is Here. Can you take 30 seconds to sign … [Read more...]
Editorial Note: Many people have wonderful responses to Humira and other biologic drugs like Enbrel (Phil Mickelson in the case of Enbrel). Rheumatoid Arthritis, Crohn's Disease and the other conditions these drugs were first used for are debilitating disorders that need a potent treatment. But if a drug is potent it will have the capacity to cause significant harms. Lots of people take part in … [Read more...]
Editorial Note: AbbVie's current legal action against the European Medicines Agency's policy on access to clinical trial data led to the idea of an AbbVie - getting people on any drugs at all, especially new drugs and in particular biologicals, to do two things: report any of the effects they are having on RxISK.org & sign the petition below. AbbVie applied to block access to two … [Read more...]
Three weeks ago Johanna Ryan and Kim Witczak wrote a letter to Stacy London about Humira and AbbVie. They were hoping for a response but there has been none so far. There’s Something About Stacy Stacy London of What Not to Wear fame has a lot going for her. She is a successful business woman, style guru and role model for women around the world. AbbVie must be delighted to have her partner … [Read more...]
Editorial Note: This post in the AbbVie series is by Johanna Ryan from the RxISK Community Advisory Board I recently read a legal complaint filed against AbbVie by a New York woman named Cynthia Di Bartolo. She’s a successful corporate lawyer who had undergone various treatments for psoriasis over the years, including medications and ultraviolet light therapy. In November 2008 she started … [Read more...]
This post stands in stark contrast to EU-nuch in the Humira-m. There could not be a greater contrast between the way companies now sell drugs globally and the way they attempt to restrict the reporting of adverse events. The infographic below from Kayla brings out the point. Sales are now global. AbbVie's plans for Humira and the plans other companies have for their Biologicals will now … [Read more...]
No such thing as being 'European' There is no such thing as being European when you take a drug like Humira or Depakote and something goes wrong. When something goes wrong on their drug, companies go to extraordinary lengths to make it almost impossible for doctors or patients to report adverse events. It’s part of a larger mission to transform what were poisons to be used with care, into … [Read more...]
Editorial Note: I have to thank Ken Spriggs for pointing out the Humira in Ulcerative Colitis Review site. For anyone interested in AbbVie-ing and in Humira this site offers some sobering reading. Humira in Ulcerative Colitis Reviews With the recent approval of Humira (Adalimumab) by the FDA, there is a growing need for ulcerative colitis patient reviews of their experiences with this … [Read more...]
Editorial Note: This post is by Ken Spriggs, who wrote the second ever RxISK story - on Azathiopine. This should be revisited in the light of the AbbVie Campaign. The current post is taken from his ongoing blog on Crohn's Disease - a condition that is high on the target list for the makers of biologicals including AbbVie and Humira. Drug side effect ratios explained This is the second part in a … [Read more...]
Editorial Note: An article in Forbes this week suggested Humira is set to become the biggest selling drug of all time. The timeline below, found by Harriet Rosenberg on the JusticeSeekers' website, covers the timeline of its elevation to the blockbuster Hall of Fame. This post and several to come are part of a sequence outlining how we can all help make Humira a better medicine by use of an … [Read more...]
The idea of a Boycott is an Irish invention. During the Land Wars in 1880, when Colonel Boycott on behalf of Lord Erne unscrupulously evicted tenants who didn't pay rent following a bad harvest, no one moved in to rent the vacant farms. Everyone refused to talk to Boycott. He was ostracised completely. The tactic worked so well that within months the Times of London was talking about Boycotts as a … [Read more...]
Editorial note: this post is by Dee Mangin .... just when you were looking at pancreatic cancer on Januvia and Byetta. Sugar Sugar: Less is not More Most people with diabetes now have type 2 diabetes. But for most people the high blood sugar called type 2 diabetes is not a disease. It is a risk factor. Just like blood pressure and cholesterol, the person sitting next to you with a higher blood … [Read more...]
After its launch in the late 1950s, Upjohn’s Orinase (tolbutamide) became the first blockbuster hypoglycemic (blood sugar lowering) drug. Its success was born of failure. It wasn’t a replacement for insulin. Even if used early, it didn’t stop people from becoming insulin dependent. But attempts to create an early use market led to a focus on raised blood sugar levels and the creation of Type 2 … [Read more...]
Editorial Note: This is a press release for a potentially important development in medicine. You can access your copy of the RIAT Act here and an assessment of its likely significance here. Restoring Invisible and Abandoned Trials (RIAT) “to correct the scientific record” Sponsors and researchers will be given one year to act before independent scientists begin publishing the results themselves … [Read more...]
Still, you take the medication as prescribed. At first you imagine your body may adjust or the pills will come to understand you. It is no use. From Virginia Chase Sutton: Lithium and the Absence of Desire. Patient engagement Patient engagement is one of the mantras of current healthcare improvement efforts. Medical students and junior doctors likely think they are doing it better than … [Read more...]
Editorial Note: This is the ninth piece or final third of the final triptych in the Lasagna trilogy of triptychs that started with Not So Bad Pharma and runs through to Marilyn's Curse. Marilyn died of an overdose of barbiturate sleeping pills (Tragedy). A bystander, Lou Lasagna, noted she had been denied access to a sleeping pill that was safe in overdose, the first pill of any sort that had … [Read more...]
Editorial Note: This an unexpected eighth part to the Lasagna Trilogy that started with Not So Bad Pharma and runs through to Witty A: Report to the President. Ondine Ondine was a nymph whose lover swore that his every waking breath was a testimony to his love of her. Finding him unfaithful, she cursed him – should he fall asleep he would stop breathing. Marilyn died of an overdose of … [Read more...]
Editorial Note: This was to be the last in the Lasagna posts that began with Not So Bad Pharma, April Fool, Tragedy of Lou Lasagna, Empire of Humbug: Bad Pharma, Empire of Humbug 2, and Brand Fascism. But the series will continue into Marilyn's Curse and When does Yes Mean No. Faced with questions about the $3 Billion fine imposed on GSK – is it just the cost of doing business? Andrew Witty … [Read more...]
Editorial Note: This is the sixth in the Lasagna series of posts that began with Not So Bad Pharma, April Fool, Tragedy of Lou Lasagna, Empire of Humbug: Bad Pharma and will continue through to Witty A: Report to the President. Faced with questions about the $3 Billion fine imposed on GSK – Is it just the cost of doing business? Andrew Witty, GSK's CEO, snapped back: “Although corporate … [Read more...]
Editorial Note: This is the fifth is the Lasagna series of posts that began with Not So Bad Pharma, April Fool, Tragedy of Lou Lasagna, Empire of Humbug: Bad Pharma and will continue through to Brand Fascism and Witty A: Report to the President. In 1954 soon after his article with Beecher put the placebo on the map, Lasagna was recruited from Harvard to Hopkins. Beecher pleaded with him to stay … [Read more...]
Editorial Note: This is the fourth in the Lasagna series of posts - Not So Bad Pharma, April Fool and Tragedy. It will be followed by The Empire of Humbug: Not so Bad Pharma, Brand Fascism & Witty A: Report to President. The first RCT In 1956, two of the creators of the modern RCT, Lou Lasagna and Michael Shepherd, met. The randomization in randomized placebo controlled trials came from … [Read more...]
Editorial Note: This is the 3rd of 6 posts. The first two are Not So Bad Pharma, & April Fool in Harlow. The rest will be The Empire of Humbug 1 & 2 and Brand Fascism. There is an independent debate on some the issues, including my writing style, at Hearing Voices on 1boringoldman. In 1956, Lou Lasagna was on his way to being the most famous doctor in the United States. His career had … [Read more...]
This is the second of a series of six posts that began with Not So Bad Pharma and will continue with The Tragedy of Lou Lasagna, The Empire of Humbug 1, The Empire of Humbug 2 & Brand Fascism. To celebrate May Fool's Day last year The Scientist ran an article on Data Diving. This featured the work of Peter Doshi and Tom Jefferson and their efforts to get clinical trial data on Tamiflu from … [Read more...]
The invitation from the London Review of Books to review Ben Goldacre’s Bad Pharma™ reads: “We were unsure, at first, what a review could add that isn't already in the book - scrappy summaries and bits of praise are not for us. The book is of sufficient importance that the main thing is to get someone who knows what they're talking about to present the material confidently.. frame the … [Read more...]
This post was written by Alan Cassels and first appeared in Focus magazine online in early March. The full version is here. Alan was one of the creators of the Selling Sickness, or disease mongering idea. His recent book is "Seeking Sickness: Medical Screening and the Misguided Hunt for Disease. There is an editorial comment below. A year ago this month - March 28, 2012, to be exact. British … [Read more...]
Dr. David Healy is an internationally respected psychiatrist, psychopharmacologist, scientist, and author. A professor of Psychiatry in Wales, David … [Read More...]
In 1962 a sleeping pill called thalidomide caused a horrific drug disaster whose emblematic images of limbless and handicapped babies born to distraught mothers linger to this … [Read More...]
